Viral hepatitis, caused by any of the five hepatotropic viruses, i.e., hepatitis A virus (HAV), hepatitis B virus (HBV), hepatitis C virus (HCV), hepatitis D virus (HDV), and hepatitis E virus (HEV), represents a major health problem worldwide.Its prevalence is highest in some parts of Africa, South America, Romania, Russia and the Mediterranean region included Southern.
In Northern India, the prevalence of hepatitis D in HBsAg-positive individuals from New Delhi was reported to be 8.1% in 1996 and 10.6% in 2005. This virus is only seen in individuals affected by hepatitis B. Majority of HDV infections are acquired through parenteral and sexual routes, which is similar to Hepatitis B. It has been estimated that ~5% of the HBV carriers are also co-infected with HDV, resulting in ~15 million people infected with HDV worldwide. The picture is similar to Hepatitis B but is more severe. The treatment of Hepatitis D is linked to treatment of Hepatitis B.
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